Publications & White Papers
The Argos® Monitor and the Multi-Beat™ Analysis algorithm have been clinically validated at well-established medical centers across the globe.
Publications on the Argos Monitor
- Key finding: In comparison with CO measured by the PAC, the Argos device proved to be more accurate than the FloTrac device in CO trending and absolute CO measurement in patients undergoing off-pump coronary artery bypass surgery.
Mukkamala R, Kohl BA, Mahajan A. Comparison of accuracy of two uncalibrated pulse contour cardiac output monitors in off-pump coronary artery bypass surgery patients using pulmonary artery catheter-thermodilution as a reference. BMC Anesthesiol (2021).
- Key finding: The multi-beat analysis (MBA) demonstrated good performance in estimating the CO variations during hemodynamic challenges compared to TED, even when vasopressors were used.
Le Gall, A., Vallée, F., Joachim, J. et al. Estimation of cardiac output variations induced by hemodynamic interventions using multi-beat analysis of arterial waveform: a comparative off-line study with transesophageal Doppler method during non-cardiac surgery. J Clin Monit Comput (2021).
- Key finding: The concordance rate for CO changes between PATD-CO and MBA-CO was 89% for cardiac surgical patients.
Saugel B, Heeschen J, Hapfelmeier A. et al. Cardiac output estimation using multi-beat analysis of the radial arterial blood pressure waveform: a method comparison study in patients having off-pump coronary artery bypass surgery using intermittent pulmonary artery thermodilution as the reference method. J Clin Monitoring and Computing (2019).
- Key finding: CO estimations by multi-beat analysis of the radial arterial blood pressure waveform (Argos Monitor) show 88% agreement compared with CO measured by intermittent PATD for post-surgical ICU patients.
Greiwe G, Peters V, Hapfelmeier A. et al. Cardiac output estimation by multi-beat analysis of the radial arterial blood pressure waveform versus intermittent pulmonary artery thermodilution: a method comparison study in patients treated in the intensive care unit after off-pump coronary artery bypass surgery. J Clin Monitoring and Computing (2019).
- Key finding: 18.5% calibrated CO error compared to pulmonary artery catheter (single bolus thermodilution) in 184 critically ill patients.
Zhang G and Mukkamala R. Continuous and minimally invasive cardiac output monitoring by long time interval analysis of a radial arterial pressure waveform assessment using a large, public intensive care unit patient database. Br J Anaesth, 2012;109(3):339–344.
- Key finding: Reliable tracking of CO reductions in 129 healthy humans during central hypovolemia.
Reisner AT, Xu D, Ryan KL, Convertino VA, Rickards CA and Mukkamala R. Monitoring non-invasive cardiac output and stroke volume during experimental human hypovolaemia and resuscitation. Br J Anaesth, 2011;106(1):23-30.
- Key finding: 15.1% calibrated CO error compared to Doppler ultrasound in 10 healthy humans during drug and postural interventions.
Lu Z and Mukkamala R. Continuous cardiac output monitoring in humans by invasive and noninvasive peripheral blood pressure waveform analysis. J Appl Physiol, 2006;101:598-608.
- Key finding: 12.9% calibrated CO error compared to aortic flow probe in 6 animals during drug and volume interventions.
Mukkamala R, Reisner AT, Hojman HM, Mark RG, Member S, Cohen RJ. Continuous Cardiac Output Monitoring by Peripheral Blood Pressure Waveform Analysis. IEEE Trans Biomed Eng. 2006;53(3):459-467.
- Arterial Blood Pressure Waveform Based Cardiac Output Analysis Corelates with Continuous Pulmonary Artery Thermodilution In Post Cardiac Surgery Intensive Care Unit Patients Including Those With Arrhythmia
- An analysis of response times for detection of changes in cardiac output in post operative cardiac surgery patients